Greg has Susie Essman in the SiriusXM studios in New York for this special podcast. They start off with some talk about books, what it's like writing them, and how the subtitles is very important, and segue nicely from that discussion into why Greg is nuts, and why Susie can't blame her teenagers for being crazy.
They talk more about Greg's brain and why it is the way it is, what he takes for it, and how that affects him. They get into religion talk, about how Catholic shame is very difficult to get rid of.
They congratulate newly engaged Jim McClure on proposing to his girlfriend, and discuss his relationship a little bit, before all three of them in the studio play the worst round of Liar's Poker in the history of the podcast.
They discuss Susie's first experience with a penis, and how she discovered years after the fact what it really meant, Greg asks Susie lots of questions about a women's anatomy, and they wrap up the show with a game of Rank 'Em.