Chappelle’s Show co-creator Neal Brennan talks about his early days in Greenwich Village working at a comedy club and his recent success as a standup, IFC show host and director.
From Childrens Hospital, Human Giant and The League, Rob Huebel asks Greg whether or not he should reproduce.
From FX’s “Married” and Adult Swim, comedian Brett Gelman denies being a hipster and talks about Greg’s 16th anniversary.
Boston wise-ass Nick Di Paolo returns to talk politics and stand-up comedy, following his awesome appearance on the show in January.
From Ray Donovan and The Thin Red Line, Dash Mihok takes us down his road less traveled.
Star of “The Office” Kate Flannery takes us from her dad’s tavern in Philly to the set of one of the best sitcoms in the last 20 years. God loves the Irish.
NPR superstar and author Sandra Tsing Loh walks Greg through how he will handle his wife’s eventual menopause and his daughter's fertility cloud.
Filmmaker Adam Goldberg, one of the stars of The Jim Gaffigan Show, talks to Greg about The Beach Boys and filming with Elvis Costello.
Colin Quinn hangs out and reminds us all that chivalry is not dead but Manhattan may be. Awesome episode.
Cristela Alonzo from the ABC sitcom Cristela listens to Greg rant about Germans while giving the Irish a free pass. It's the Potato Salad Wars.
From the Golden Globe-winning series Transparent, the marvelous Amy Landecker bonds with Greg about their identical lives as children of hard-living radio DJs in the '70s. Shocking!
SiriusXM superstar Jason Ellis encourages Greg to take a walk on the wild side and swing by the sex toy shop.
Greg’s old friend, the sexy Suzy McCoppin, details the dark side of Internet dating and her experience with a foot fetishist.
Broadcasting queen Alison Rosen has Greg over to her house and shows why she is one of the best in the business.
Comedy wildebeest Jim Breuer swings by the studio to talk about his first TV appearance with Greg on A&E's "Comedy on the Road."
From the new Entourage movie, Haley Joel Osment returns to the show and takes calls. You are never going to guess what you guys asked.